Birgit Rathkolb Selected Research

Mitochondrial DNA (mtDNA)

1/2022

Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction.

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Birgit Rathkolb Research Topics

Disease

8	Body Weight (Weight, Body) 10/2018 - 03/2007
7	Type 2 Diabetes Mellitus (MODY) 01/2020 - 01/2013
6	Hyperglycemia 10/2020 - 02/2008
6	Insulin Resistance 10/2018 - 05/2007
5	Kidney Diseases (Kidney Disease) 01/2022 - 05/2007
5	Inflammation (Inflammations) 01/2020 - 05/2011
5	Juvenile gout 04/2014 - 11/2009
4	Obesity 12/2019 - 03/2016
3	Non-alcoholic Fatty Liver Disease 01/2020 - 01/2013
3	Neoplasms (Cancer) 01/2020 - 01/2013
3	Diabetes Mellitus 01/2019 - 02/2008
3	Fibrosis (Cirrhosis) 01/2016 - 12/2012
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 12/2021
2	Iron Overload 01/2020 - 05/2007
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2020 - 04/2014
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2018 - 01/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2016 - 08/2007
2	Hypertension (High Blood Pressure) 12/2016 - 12/2012
2	Hyperplasia 01/2016 - 10/2013
2	Bartter Syndrome (Syndrome, Bartter) 08/2014 - 06/2010
2	Metabolic Bone Diseases (Osteopenia) 08/2012 - 06/2010
1	Vision Disorders (Hemeralopia) 10/2021
1	Nervous System Diseases (Neurological Disorders) 10/2021
1	Weight Loss (Weight Reduction) 07/2021
1	Hemorrhage 10/2020
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020
1	Ataxia (Dyssynergia) 01/2020
1	Neuroinflammatory Diseases 01/2020
1	Iron Deficiencies 01/2020
1	Frontotemporal Dementia (Semantic Dementia) 01/2020
1	Hepatocellular Carcinoma (Hepatoma) 01/2020
1	Seizures (Absence Seizure) 01/2020
1	Methylmalonic acidemia 01/2020
1	Intellectual Disability (Idiocy) 01/2019
1	Pain (Aches) 01/2019
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2019
1	Proteostasis Deficiencies 01/2019
1	Hemolytic Anemia 01/2019
1	Glucose Intolerance 10/2018
1	Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia 01/2018
1	Stroke (Strokes) 01/2018
1	Ischemic Stroke 01/2018
1	ZAP70 deficiency 01/2018
1	Laron Syndrome (Syndrome, Laron) 01/2018
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2018

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2014
8	Insulin (Novolin)FDA Link 01/2020 - 05/2007
7	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 01/2018 - 01/2005
7	Urea (Carbamide)FDA LinkGeneric 08/2017 - 01/2005
6	IronIBA 10/2021 - 05/2007
6	Glucose (Dextrose)FDA LinkGeneric 10/2020 - 01/2013
5	CholesterolIBA 10/2018 - 01/2005
5	UromodulinIBA 04/2014 - 11/2009
4	LipidsIBA 01/2017 - 11/2009
3	Biomarkers (Surrogate Marker)IBA 12/2019 - 08/2012
3	Triglycerides (Triacylglycerol)IBA 10/2018 - 11/2009
3	Erythropoietin FDA Link 01/2018 - 01/2009
3	Transcription Factors (Transcription Factor)IBA 01/2017 - 01/2009
2	SodiumIBA 07/2021 - 12/2012
2	Transfer RNA (tRNA)IBA 01/2020 - 01/2019
2	Phosphatidylcholines (Phosphatidylcholine)IBA 12/2019 - 12/2012
2	Hormones (Hormone)IBA 01/2019 - 10/2014
2	EnzymesIBA 01/2019 - 09/2009
2	Pharmaceutical PreparationsIBA 10/2018 - 01/2017
2	Nonesterified Fatty Acids (NEFA)IBA 10/2018 - 11/2009
2	Blood Glucose (Blood Sugar)IBA 01/2018 - 05/2007
2	Streptozocin (Streptozotocin)FDA Link 01/2018 - 01/2016
2	Metformin (Glucophage)FDA LinkGeneric 01/2018 - 01/2015
2	BezafibrateIBA 01/2017 - 01/2016
2	SaltsIBA 12/2016 - 06/2010
2	Member 1 Solute Carrier Family 12IBA 08/2014 - 06/2010
2	Uric Acid (Urate)IBA 10/2013 - 11/2009
2	ATP-Binding Cassette Transporters (ABC Transporters)IBA 08/2013 - 12/2012
2	AldosteroneIBA 12/2012 - 01/2011
1	Mitochondrial DNA (mtDNA)IBA 01/2022
1	exodeoxyribonuclease IIBA 01/2022
1	Exonucleases (3' 5' Exonuclease)IBA 01/2022
1	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 12/2021
1	DisulfidesIBA 10/2020
1	Thromboplastin (Tissue Factor)IBA 10/2020
1	Fetuin-BIBA 01/2020
1	MethyltransferasesIBA 01/2020
1	DipeptidesIBA 01/2020
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2020
1	Ferritins (Ferritin)IBA 01/2020
1	Methylmalonyl-CoA MutaseIBA 01/2020
1	poly(glycyl-alanyl)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 01/2020
1	Transferrin Receptors (Transferrin Receptor)IBA 01/2020
1	AcidsIBA 12/2019
1	Phospholipids (Phosphatides)FDA LinkGeneric 12/2019
1	Alanine (L-Alanine)FDA Link 12/2019
1	Triose-Phosphate Isomerase (Triosephosphate Isomerase)IBA 01/2019
1	Somatotropin Receptors (Growth Hormone Receptor)IBA 01/2018
1	Messenger RNA (mRNA)IBA 01/2018
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2018
1	Neuroprotective AgentsIBA 01/2018

Therapy/Procedure

1	Euthanasia (Mercy Killing) 01/2020
1	Muscle Denervation 01/2020